Mitral valve prolapse tends to occur more commonly in individuals with Klinefelter Syndrome than those without, however this heart condition may pose no medical problems, or it could be severe enough to require surgery. The earlier in life that KS symptoms are recognized and treated, the more likely it is that the symptoms can be reduced or eliminated.2 It is especially helpful to begin treatment by early puberty. Treatment Options for Klinefelter Syndrome . We want you to have one resource to turn to for facts presented in such a way that they are easy to understand. L'individu est alors de caractère masculin, mais infertile. These tests are not typically medically verified and should not be used to make medical decisions. Get the latest public health information from CDC: https://www.coronavirus.gov While there is no cure for sex chromosome changes caused by Klinefelter syndrome, treatments can help minimize effects, especially when … The list of treatments mentioned in various sources for Klinefelter syndrome includes the following list. Because these tests come with a small risk of miscarriage, their use is very conservative. About Klinefelter Syndrome Klinefelter Syndrome (KS) is a condition that occurs in men who have one or more extra X chromosomes. Klinefelter's Syndrome, which affects 1 in 500 to 1 in 1000 live births, is a sex chromosomal genetic disorder where the affected males have an extra X chromosome. It’s believed that half the time the error originates in the mother’s egg and the other half is due to the father’s sperm. Boys with Klinefelter syndrome may also have difficulty fitting in socially and interacting with their peers as personality traits often include being shy and quiet. We take the information we share seriously. The earlier treatment begins, the better the outcomes. Since that time, doctors and researchers have come to learn it’s the most common chromosomal abnormality affecting newborn males. Chromosomes are tiny, but very important, structures in every cell. Males with Klinefelter syndrome should be seen by a team of health care providers. They are able to lead normal lives that are fulfilling and well adjusted with few symptoms. This treatment should begin at puberty or as soon after as possible. It’s one of the most common types of cosmetic surgery for men. Individuals with this condition might have lower self-esteem than their peers and need additional emotional support. Learn more about Klinefelter syndrome, including how it affects men's hormone health and what treatment options are available. However, treatment can bring benefits at any age. Physical therapy is used to build strength and motor skills. Contrary to research results released decades ago, current research shows that XXY males are no more likely than other males to have serious psychiatric disorders or to get into trouble with the law.10. Diagnosing Klinefelter syndrome based on symptoms alone can be difficult, and there is no standard guideline for clinical diagnosis. What is Klinefelter syndrome? Klinefelter syndrome: Is the Diagnosis Correct? Approximately 5% of Klinefelter syndrome cases detected at amniocentesis r… Men with this syndrome tend to have enlarged breast tissues. Men who have Klinefelter syndrome also have an increased risk for autoimmune disorders such as lupus, rheumatoid arthritis and Sjogren's syndrome. Once the child reaches puberty other physical signs can appear often due to low levels of testosterone. It occurs when a male baby is born with more than required or extra X chromosomes. There’s also an increased frequency of other diseases and medical conditions associated with Klinefelter syndrome. Endodontic treatment in three taurodontic teeth associated with 48,XXXY Klinefelter syndrome: A review and case report. In this case, if the Klinefelter patient wishes to reduce the social anxiety of having enlarged breasts, the only current treatment is surgery. Speech therapy should be started as soon as possible to maximize its effectiveness. Most boys born with Klinefelter syndrome can lead normal productive lives with proper treatment and support. This type of therapy may be needed to build social skills and manage emotions. HRT Doctors Group has extensive experience with Klinefelter Syndrome Treatment using Testosterone Replacement Therapy. Boys and men with Klinefelter syndrome have a 2-40 fold increased risk of getting a bone fracture. Research into men’s experience of pregnancy following fertility treatment 20th September 2020 Guy’s Hospital First Klinefelter’s Syndrome (KS/XXY) Adolescent Clinic 27th August 2020 Your views on intersex community platforms – Dublin University survey 23rd August 2020 Klinefelter syndrome is classed as a disability when a child has learning disabilities. More research on this is needed before a consensus can be established. Management of Klinefelter Syndrome: The management of Klinefelter syndrome in the Allopathy medicine system is done with Psychological counseling, Fertility treatment, Breast tissue removal, and Testosterone replacement therapy. Receiving a diagnosis of Klinefelter Syndrome might be surprising. Klinefelter syndrome is a condition that requires a multidisciplinary treatment approach involving one or more of the following specialists: Mild cases of Klinefelter syndrome may require no treatment. What Is Klinefelter Syndrome? It is important to know that your genes are not your destiny. HRT DOCTORS GROUP HAS CREATED A SPECIFIC LOWER-COST KLINEFELTER SYNDROME TREATMENT PROTOCOL: Initial Hormone Blood Test + Doctor Consultation: $79.95 (Note: This is a one-time fee) Monthly Medical Rx Protocol: $155.95 *Details: Includes unlimited access to … A recent Danish study indicated that Klinfelter syndrome was present in 153 per 100,000 babies tested.3. In many cases, men with Klinefelter syndrome can’t father a child naturally on their own. Come follow the journey. Because symptoms of Klinefelter syndrome (KS) can sometimes be very mild, many people are never diagnosed or treated. What are the treatments for symptoms in Klinefelter syndrome (KS)? For males whose testosterone level is low to normal, the benefits of taking testosterone are less clear than for when testosterone is very low. Kleinfelter syndrome facts author: John P. Cunha, DO, FACOEP. There is no way to prevent Klinefelter syndrome. Your doctor will likely do a thorough physical exam and ask detailed questions about symptoms and health. Research into men’s experience of pregnancy following fertility treatment 20th September 2020; Guy’s Hospital First Klinefelter’s Syndrome (KS/XXY) Adolescent Clinic 27th August 2020; Your views on intersex community platforms – Dublin University survey 23rd August 2020; The emotional impact of male infertility 4th July 2020 Fertility Treatment. Our review of these tests is meant to help explain what you can, and more importantly what you can NOT, expect to learn or decide from their results. Always seek professional medical advice about any treatment or change in treatment plans. Read more about our partner Cure Rare Disease and the fight against Duchenne’s. Endodontic treatment in three taurodontic teeth associated with 48,XXXY Klinefelter syndrome: A review and case report. However there are treatments available for the problems associated with the condition. However, these symptoms do not occur in everyone with this condition. Klinefelter syndrome is a genetic condition affecting males, and it often isn't diagnosed until adulthood.Klinefelter syndrome may adversely affect testicular growth, resulting in smaller than normal testicles, which can lead to lower production of testosterone. With regard to education, some boys with KS will qualify to receive state-sponsored special needs services to address their developmental and learning symptoms. There are also Klinefelter support groups for parents as well. Is testosterone therapy right for every XXY male? Klinefelter syndrome (KS), also known as 47,XXY is the set of symptoms that result from two or more X chromosomes in males. Klinefelter's syndrome is a set of symptoms resulting from two or more X chromosomes in males. There is a study that claims that timely and planned support allotted to young men with this condition can restore present poor psychosocial effects. Klinefelter syndrome is the presence of an extra X chromosome in a male. 2. Advances in assistive reproductive technology (ART) have made it possible for some men with KS to conceive. Take your time moving through the sections and feel free to read it a few times. Seeing a psychologist or psychiatrist can help alleviate emotional and mental problems associated with having Klinefelter syndrome. Early intervention can prevent some symptoms from occurring. For these males, supplemental testosterone may not be suitable. Klinefelter is a genetic disorder that affects males; this is due to when a male born with an extra copy of X chromosome, which causes infertility, low testosterone and other abnormalities such as breast development. Men with Klinefelter syndrome can now have children, if they want, with new forms of in-vitro fertilisation. Diagnosing Klinefelter syndrome in utero or at birth is rare. Additionally, up to 1 in 4 children with Klinefelter syndrome are diagnosed with a psychiatric disturbance. There's no cure for Klinefelter syndrome, but some of the problems associated with the condition can be treated if necessary. Hormone testing. When we focus on the sex chromosomes, we see that typically women have two X chromosomes and men have an X and a Y chromosome. As men, most guys with Klinefelter syndrome can have sex, usually with the help of testosterone treatment. Chromosomes carry all of our genes, and genes give instructions for our bodies to grow and function. The laboratory will generate a karyotype (picture of chromosomes) and look for the aneuploidy (too many or too few chromosomes). What is the treatment for Klinefelter syndrome? Let us start by saying, Klinefelter is no one's fault. Klinefelter syndrome is one of the genetic disorders in males. There is no cure for KS (Klinfelter Syndrome). Treatment involves the targeted administration of male hormones (androgens), such as testosterone enanthate, cypionate, or androgel. Due poor or no sperm count, the majority of the men with Klinefelter syndrome are found to be infertile. People typically have 46 chromosomes in each cell, two of which are the sex chromosomes. For most individuals with Klinefelter Syndrome, the signs and symptoms tend to be mild, often going undiagnosed until puberty or adulthood. For this procedure, a surgeon removes sperm from the testes and places one sperm into an egg. Fractures are another regular occurrence due to weakened bones (osteoporosis). Klinefelter syndrome treatment. Most males have one Y and one X chromosome. Testosterone therapy can help with many of the symptoms of Klinefelter syndrome. Men with some sperms in their semen, the intracytoplasmic sperm injection (ICSI) can be used to impregnate their partners. Klinefelter's syndrome lifestyle effects are minimal for many men. Klinefelter syndrome treatment with homeopathy is also prominent for treating secondary symptoms. It’s best to begin testosterone replacement therapy at the time of puberty so that boys develop as normally as possible. Connect with our licensed genetic counselors now. Testosterone replacement therapy can be administered by injection, patch, pill or topical cream. The syndrome can affect boys and men at different stages of life and their physical, language, and social development. Klinefelter syndrome and medical treatment: hypogonadism and beyond ... costs and benefits of such an approach in KS.24 The genetic background of KS is the presence RI H[WUD ; FKURPRVRPH V ZLWK RI DIIHFWHG individuals having the 47,XXY karyotype and the remaining cases presenting with either 47,XXY/46 XY mosaicism or multiple X chromosome aneuploidy, often also with additional Y … Individuals with Klinefelter Syndrome will have low levels of testosterone. Individuals with this condition should see endocrinology to discuss testosterone therapy. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontolog y , 105 (5), 670-677. The first medical description of Klinefelter syndrome was in 1942. Living with XXY became a NonProfit 501(c)(3) Charitable organization on November 6th, 2019. Some school districts and health centers might also offer these types of skill-building programs or classes. Treating Language and Learning Symptoms Klinefelter syndrome is a genetic condition that affects males. For this reason, it is important to talk to your doctor about any medical symptoms or genetic tests you are considering. An estimated 53-55% of conceptions affected with Klinefelter syndrome are expected to survive to term.4. Following the 1st International Workshop on the Klinefelter Syndrome in 2010 (Juul et al., 2011), the 2nd IWKS took place in M€unster, Germany from March 10 to 12, 2016 and was organized by the Centre of Reproductive Medicine and Andrology of the University of M€unster. We have a new Website. Blood or urine samples can reveal abnormal hormone levels that are a sign of Klinefelter syndrome. Klinefelter Syndrome Definition, Klinefelter Syndrome Causes, Klinefelter Syndrome Symptoms, Klinefelter Syndrome Complications, Klinefelter Syndrome Surgery in India, Klinefelter Syndrome Surgery Cost, Klinefelter Syndrome Treatment in India, Klinefelter Syndrome Hospital in India, Klinefelter Syndrome best Surgeon in India Variants of … Often, symptoms are subtle and subjects do not realize they are affected. When adult men have breasts, they are at higher risk for breast cancer than other men and need to be checked for this condition regularly. Come follow the journey. It’s also commonly referred to as XXY syndrome or 47, XXY. There is a large community of families with this condition who can provide guidance and support. The odds may be improved by freezing sperm in adolescence when the sperm is healthier. There are even fertility treatments available for men with Klinefelter syndrome as most men with this condition have no or very little sperm. Many males consist of one X and one Y chromosome and an extra chromosome can cost a male with physical traits which are inappropriate for males. This syndrome is non-curable; however there are available treatments to cure the symptoms brought by Klinefelter's syndrome. This treatment should begin at puberty or as soon after as possible. Klinefelter syndrome is the presence of an extra X chromosome in a male. Fertility Treatment. When they enter school they might experience some learning disabilities such as mild delays in their speech and language development or difficulty reading. 1. But this type of treatment is not suitable because surgery causes greater pain and also costs higher. The primary features are infertility and small poorly functioning testicles. Stevens-Johnson Syndrome Genetic Disorder, Duchenne Muscular Dystrophy: Genetic Disorder. Researchers have estimated that up to 75% of males with Klinefelter syndrome are never diagnosed 2. and the vast majority that are receive a delayed diagnosis that doesn’t occur until puberty or later. Treatment may include: Testosterone replacement: About half of people with … Cases where three or more X chromosomes are present are much less common, affecting just 1 in 50,000 newborn males. Androgen therapy (types of testosterone) is the most common form of treatment for Klinefelter syndrome and can have a number of positive effects, including improving sex drive, promoting hair growth, increasing muscle strength and energy levels, and reducing the likelihood of osteoporosis. While life expectancy isn’t believed to be heavily impacted by Klinefelter syndrome, living with the condition can be difficult. This syndrome affects the testicular growth, results in smaller testicles and may cause reduced muscle mass, reduced facial and body hair. All individuals with Klinefelter Syndrome will have a Y chromosome which means they will all be males. What is a Haplotype? Most individuals with this condition will lead healthy and meaningful lives. You can find Klinefelter syndrome support groups through your primary care physician. When a diagnosis is made, treatment is based on the signs and symptoms present in each person, especially the problems related to hypogonadism, gynecomastia, and psychosocial problems. In this issue of the Journal, Zganjar et al. 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No approved drug treatment exists for this condition of over-developed breast tissue, termed gynecomastia. General practitioners. Le syndrome de Klinefelter ou 47,XXY est une aneuploïdie qui se caractérise chez l'homme par un chromosome sexuel X supplémentaire. Assisted reproductive technology (ART) procedures can help some men with Klinefelter syndrome overcome infertility issues. Sa formule chromosomique s'écrit « 2N=47, XXY », et non plus « 2N=46 ». One of these is through testosterone treatment. There are genetic tests that can diagnose Klinefelter syndrome. En Español. Always seek professional medical advice about any treatment or change in treatment plans. Is Klinefelter syndrome dominant or recessive? For instance, it is possible that the resulting child might have the XXY condition. 1. Between 95% and 99% of XXY men are infertile because they do not produce enough sperm to fertilize an egg naturally. Boys and men with KS can benefit by visiting therapists who are experts in areas such as coordination, social skills, and coping. This is one of the most common Klinefelter syndrome treatments since many of the symptoms stem from low testosterone. This can be managed by assisted reproductive procedure and may make possible to … Not all males with XXY condition benefit from testosterone therapy. Some health care providers recommend surgery—called mastectomy (pronounced ma-STEK-tuh-mee)—to remove or reduce the breasts of XXY males. Testosterone therapy can help with many of the symptoms of Klinefelter syndrome. Additionally, individuals with Klinefelter Syndrome may struggle with mental health. Klinefelter syndrome is a condition that requires a multidisciplinary treatment approach involving one or more of the following specialists: Pediatricians. AIM: The aim of this analysis was to evaluate health outcomes and costs associated with life-long TRT in patients suffering from Klinefelter syndrome and late-onset hypogonadism (LOH). Upwards of 75% of children with it have a learning disability. While ART procedures have improved in recent years, there’s still no guarantee they will work. Early detection and treatment improves your or your child’s ability to lead a productive life. Learn more about the causes, symptoms, and treatment of Klinefelter syndrome. Infertility specialists. And for goodness sake, don't smoke. XXY males who are thinking about mastectomy should discuss all the risks and benefits with their health care provider. However, numerous clinical studies have failed to show the relationship between breast cancer and gynecomastia. Breast reduction surgery can be used to remove excess breast tissue. Treating Social and Behavioral Symptoms. There are various environmental and genetic factors working together to shape you. 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